ASPP2 enhances Oxaliplatin (L-OHP)-induced colorectal cancer cell apoptosis in a p53-independent manner by inhibiting cell autophagy

Inactivation of p53-mediated cell death pathways is a central component of cancer progression. ASPP2 (apoptosis stimulated protein of p53-2) is a p53 binding protein that specially stimulates pro-apoptosis function of p53. Down-regulation of ASPP2 is observed in many human cancers and is associated...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Shi, Ying, Han, Yue, Xie, Fang, Wang, Anna, Feng, Xiaokun, Li, Ning, Guo, Hongliang, Chen, Dexi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369811/
https://ncbi.nlm.nih.gov/pubmed/25534115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12435
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