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Description and simulation of a physiological pharmacokinetic model for the metabolism and enterohepatic circulation of bile acids in man. Cholic acid in healthy man.

A multicompartmental pharmacokinetic model based on physiological principles, experimental data, and the standard mathematical principles of compartmental analysis has been constructed that fully describes the metabolism and enterohepatic cycling in man of cholic acid, a major bile acid. The model f...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Hofmann, A F, Molino, G, Milanese, M, Belforte, G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 1983
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6682120/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110828
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