Evidence for Two Pathways of Iodothyronine 5′-Deiodination in Rat Pituitary That Differ in Kinetics, Propylthiouracil Sensitivity, and Response to Hypothyroidism

We have studied 5′-deiodination of thyroxine (T(4)) and 3,3′,5′-triiodothyronine (rT(3)) in rat pituitary tissue in vitro, with respect to substrate specificity, reaction kinetics, effects of 6-n-propyl-2-thiouracil (PTU), and the time course of effects of thyroid hormone depletion and repletion. Re...

Celý popis

Podrobná bibliografie

Vydáno v:	J Clin Invest
Hlavní autoři:	Visser, Theo J., Kaplan, Michael M., Leonard, Jack L., Larsen, P. Reed
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1983
Témata:	Articles
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436957/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6833498/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110854
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!