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Repression of Ccr9 transcription in mouse T lymphocyte progenitors by the Notch signaling pathway

The chemokine receptor CCR9 controls the immigration of multipotent hematopoietic progenitor cells into the thymus to sustain T cell development. Post-immigration, thymocytes down regulate CCR9 and migrate toward the subcapsular zone where they recombine their T cell receptor β-chain and γ-chain gen...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Krishnamoorthy, Veena, Carr, Tiffany, de Pooter, Renee F., Akinola, Emanuelle Olumide, Gounari, Fotini, Kee, Barbara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369417/
https://ncbi.nlm.nih.gov/pubmed/25710912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402443
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