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Timely immunization subverts the development of peripheral nonresponsiveness and suppresses tumor development in simian virus 40 tumor antigen-transgenic mice.

Tolerance to tumor cell-expressed molecules and selection of cells that evade immune surveillance during tumor progression create effective barriers to immunotherapy. We investigated the cytotoxic T-lymphocyte response to simian virus 40 (SV40) tumor (T/t) antigen in two lineages of transgenic mice...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ye, X, McCarrick, J, Jewett, L, Knowles, B B
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1994
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43693/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8171012/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.9.3916
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