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Extending the translational potential of targeting NO/cGMP-regulated pathways in the CVS

The discovery of NO as both an endogenous signalling molecule and as a mediator of the cardiovascular effects of organic nitrates was acknowledged in 1998 by the Nobel Prize in Physiology/Medicine. The characterization of its downstream signalling, mediated through stimulation of soluble GC (sGC) an...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Papapetropoulos, Andreas, Hobbs, Adrian J, Topouzis, Stavros
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369253/
https://ncbi.nlm.nih.gov/pubmed/25302549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12980
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