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Insulin resistance in uremia. Characterization of insulin action, binding, and processing in isolated hepatocytes from chronic uremic rats.

We have developed a model in the rat that leads to a predictable degree of severe uremia to study the role of the liver in the insulin-resistant state of uremia. The uremic animals were euglycemic and had increased serum immunoreactive insulin when compared with their pair-fed controls. Insulin acti...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Kauffman, J M, Caro, J F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436919/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6338044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110816
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