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In Vitro Desensitization of Beta Adrenergic Receptors in Human Neutrophils. ATTENUATION BY CORTICOSTEROIDS

The receptor alterations involved in catecholamine-induced desensitization of adenylate cyclase in human neutrophils have been investigated as has the ability of hydrocortisone to modify such alterations. Incubation of human neutrophils with isoproterenol for 3 h in vitro resulted in an 86% reductio...

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Pubblicato in:J Clin Invest
Autori principali: Davies, Albert O., Lefkowitz, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436904/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6298279/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110801
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