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alpha-Thalassemia caused by an unstable alpha-globin mutant.

In a previous study, molecular cloning of the alpha-globin genes from a patient with nondeletion Hb-H disease (genotype--/alpha alpha) showed that a single nucleotide mutation (CTG to CCG) in one of the genes resulted in a leucine to proline substitution. This paper describes the approach we used to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liebhaber, S A, Kan, Y W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1983
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC436893/
https://ncbi.nlm.nih.gov/pubmed/6826718
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