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Bupropion Increases Selection of High Effort Activity in Rats Tested on a Progressive Ratio/Chow Feeding Choice Procedure: Implications for Treatment of Effort-Related Motivational Symptoms

BACKGROUND: Depression and related disorders are characterized by deficits in behavioral activation, exertion of effort, and other psychomotor/motivational dysfunctions. Depressed patients show alterations in effort-related decision making and a bias towards selection of low effort activities. It ha...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Randall, Patrick A., Lee, Christie A., Podurgiel, Samantha J., Hart, Evan, Yohn, Samantha E., Jones, Myles, Rowland, Margaret, López-Cruz, Laura, Correa, Mercè, Salamone, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368885/
https://ncbi.nlm.nih.gov/pubmed/25575584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu017
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