A Novel Respiratory Syncytial Virus (RSV) F Subunit Vaccine Adjuvanted with GLA-SE Elicits Robust Protective T(H)1-Type Humoral and Cellular Immunity In Rodent Models

BACKGROUND: Illness associated with Respiratory Syncytial Virus (RSV) remains an unmet medical need in both full-term infants and older adults. The fusion glycoprotein (F) of RSV, which plays a key role in RSV infection and is a target of neutralizing antibodies, is an attractive vaccine target for...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lambert, Stacie L., Aslam, Shahin, Stillman, Elizabeth, MacPhail, Mia, Nelson, Christine, Ro, Bodrey, Sweetwood, Rosemary, Lei, Yuk Man, Woo, Jennifer C., Tang, Roderick S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368639/
https://ncbi.nlm.nih.gov/pubmed/25793508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119509
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