Microvesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Facilitate Tubular Epithelial Cell Dedifferentiation and Growth via Hepatocyte Growth Factor Induction

During acute kidney injury (AKI), tubular cell dedifferentiation initiates cell regeneration; hepatocyte growth factor (HGF) is involved in modulating cell dedifferentiation. Mesenchymal stem cell (MSC)-derived microvesicles (MVs) deliver RNA into injured tubular cells and alter their gene expressio...

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Publicado en:PLoS One
Autores principales: Ju, Guan-qun, Cheng, Jun, Zhong, Liang, Wu, Shuai, Zou, Xiang-yu, Zhang, Guang-yuan, Gu, Di, Miao, Shuai, Zhu, Ying-jian, Sun, Jie, Du, Tao
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368636/
https://ncbi.nlm.nih.gov/pubmed/25793303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121534
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