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Neuronal Antibody Biomarkers for Sydenham’s Chorea Identify a New Group of Children with Chronic Recurrent Episodic Acute Exacerbations of Tic and Obsessive Compulsive Symptoms Following a Streptococcal Infection

Several autoantibodies (anti-dopamine 1 (D1R) and 2 (D2R) receptors, anti-tubulin, anti-lysoganglioside-GM1) and antibody-mediated activation of calcium calmodulin dependent protein kinase II (CaMKII) signaling activity are elevated in children with Sydenham’s chorea (SC). Recognizing proposed clini...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Singer, Harvey S., Mascaro-Blanco, Adda, Alvarez, Kathy, Morris-Berry, Christina, Kawikova, Ivana, Ben-Pazi, Hilla, Thompson, Carol B., Ali, Syed F., Kaplan, Edward L., Cunningham, Madeleine W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368605/
https://ncbi.nlm.nih.gov/pubmed/25793715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120499
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