Potential Biomarkers of Fatigue Identified by Plasma Metabolome Analysis in Rats

In the present study, prior to the establishment of a method for the clinical diagnosis of chronic fatigue in humans, we validated the utility of plasma metabolomic analysis in a rat model of fatigue using capillary electrophoresis-mass spectrometry (CE-MS). In order to obtain a fatigued animal grou...

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Bibliographic Details
Published in:PLoS One
Main Authors: Kume, Satoshi, Yamato, Masanori, Tamura, Yasuhisa, Jin, Guanghua, Nakano, Masayuki, Miyashige, Yukiharu, Eguchi, Asami, Ogata, Yoshiyuki, Goda, Nobuhito, Iwai, Kazuhiro, Yamano, Emi, Watanabe, Yasuyoshi, Soga, Tomoyoshi, Kataoka, Yosky
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368560/
https://ncbi.nlm.nih.gov/pubmed/25793974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120106
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