Two types of dysfunctional eighth component of complement (C8) molecules in C8 deficiency in man. Reconstitution of normal C8 from the mixture of two abnormal C8 molecules.

Restoration of hemolytic activity was examined in sera from seven unrelated eighth component of complement (C8)-deficient subjects. The sera fell into two groups, depending on whether hemolytic activity was restored by the addition of the beta-chain (group 1) or the alpha-gamma-subunit (group 2) pur...

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Udgivet i:J Clin Invest
Main Authors: Tedesco, F, Densen, P, Villa, M A, Petersen, B H, Sirchia, G
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436856/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6822660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110758
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