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Standard Sub-Thermoneutral Caging Temperature Influences Radiosensitivity of Hematopoietic Stem and Progenitor Cells

The production of new blood cells relies on a hierarchical network of hematopoietic stem and progenitor cells (HSPCs). To maintain lifelong hematopoiesis, HSPCs must be protected from ionizing radiation or other cytotoxic agents. For many years, murine models have been a valuable source of informati...

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Veröffentlicht in:PLoS One
Hauptverfasser: Povinelli, Benjamin J., Kokolus, Kathleen M., Eng, Jason W.-L., Dougher, Christopher W., Curtin, Leslie, Capitano, Maegan L., Sailsbury-Ruf, Christi T., Repasky, Elizabeth A., Nemeth, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368554/
https://ncbi.nlm.nih.gov/pubmed/25793392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120078
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