Colorectal Mucus Binds DC-SIGN and Inhibits HIV-1 Trans-Infection of CD4(+) T-Lymphocytes

Bodily secretions, including breast milk and semen, contain factors that modulate HIV-1 infection. Since anal intercourse caries one of the highest risks for HIV-1 transmission, our aim was to determine whether colorectal mucus (CM) also contains factors interfering with HIV-1 infection and replicat...

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Veröffentlicht in:PLoS One
Hauptverfasser: Stax, Martijn J., Mouser, Emily E. I. M., van Montfort, Thijs, Sanders, Rogier W., de Vries, Henry J. C., Dekker, Henk L., Herrera, Carolina, Speijer, Dave, Pollakis, Georgios, Paxton, William A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368515/
https://ncbi.nlm.nih.gov/pubmed/25793526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122020
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