Impact of Intratumoral Expression Levels of Fluoropyrimidine-Metabolizing Enzymes on Treatment Outcomes of Adjuvant S-1 Therapy in Gastric Cancer

We analyzed the expression levels of fluoropyrimidine-metabolizing enzymes (thymidylate synthase [TS], dihydropyrimidine dehydrogenase [DPD], thymidine phosphorylase [TP] and orotate phosphoribosyltransferase [OPRT]) to identify potential biomarkers related to treatment outcomes in gastric cancer (G...

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Udgivet i:PLoS One
Main Authors: Kim, Ji-Yeon, Shin, Eun, Kim, Jin Won, Lee, Hye Seung, Lee, Dae-Won, Kim, Se-Hyun, Lee, Jeong-Ok, Kim, Yu Jung, Kim, Jee Hyun, Bang, Soo-Mee, Ahn, Sang-Hoon, Park, Do Joong, Lee, Jong Seok, Lee, Ju-Seog, Kim, Hyung-Ho, Lee, Keun-Wook
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368508/
https://ncbi.nlm.nih.gov/pubmed/25793299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120324
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