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Proinflammatory microenvironments within the intestine regulate differentiation of tissue-resident CD8 T cells responding to infection

We report that oral infection with Yersinia pseudotuberculosis (Yptb) results in development of two distinct populations of pathogen-specific CD8 tissue-resident memory T (T(RM)) cells in the lamina propria (LP). CD103(–) T cells did not require transforming-growth factor-β (TGF-β) signaling, but we...

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Publicado en:Nat Immunol
Main Authors: Bergsbaken, Tessa, Bevan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368475/
https://ncbi.nlm.nih.gov/pubmed/25706747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3108
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