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Multi-Functional Regulation of 4E-BP Gene Expression by the Ccr4-Not Complex

The mechanistic target of rapamycin (mTOR) signaling pathway is highly conserved from yeast to humans. It senses various environmental cues to regulate cellular growth and homeostasis. Deregulation of the pathway has been implicated in many pathological conditions including cancer. Phosphorylation c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Okada, Hirokazu, Schittenhelm, Ralf B., Straessle, Anna, Hafen, Ernst
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368434/
https://ncbi.nlm.nih.gov/pubmed/25793896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113902
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