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Multi-Functional Regulation of 4E-BP Gene Expression by the Ccr4-Not Complex

The mechanistic target of rapamycin (mTOR) signaling pathway is highly conserved from yeast to humans. It senses various environmental cues to regulate cellular growth and homeostasis. Deregulation of the pathway has been implicated in many pathological conditions including cancer. Phosphorylation c...

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Pubblicato in:PLoS One
Autori principali: Okada, Hirokazu, Schittenhelm, Ralf B., Straessle, Anna, Hafen, Ernst
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368434/
https://ncbi.nlm.nih.gov/pubmed/25793896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113902
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