Metabolic and cellular alterations underlying the exaggerated renal prostaglandin and thromboxane synthesis in ureter obstruction in rabbits. Inflammatory response involving fibroblasts and mononuclear cells.

Unilateral ureter obstruction in rabbits produced profound changes in endogenous and exogenous renal arachidonic acid metabolism. Isolated perfused hydronephrotic kidneys (removed after 3 or 10 d of ureter obstruction) responded to bradykinin stimulation with a markedly enhanced release of prostagla...

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Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	Okegawa, T, Jonas, P E, DeSchryver, K, Kawasaki, A, Needleman, P
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1983
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6848562/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110754
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