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Oral, Nasal and Pharyngeal Exposure to Lipopolysaccharide Causes a Fetal Inflammatory Response in Sheep

BACKGROUND: A fetal inflammatory response (FIR) in sheep can be induced by intraamniotic or selective exposure of the fetal lung or gut to lipopolysaccharide (LPS). The oral, nasal, and pharyngeal cavities (ONP) contain lymphoid tissue and epithelium that are in contact with the amniotic fluid. The...

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Veröffentlicht in:PLoS One
Hauptverfasser: Maneenil, Gunlawadee, Kemp, Matthew W., Kannan, Paranthaman Senthamarai, Kramer, Boris W., Saito, Masatoshi, Newnham, John P., Jobe, Alan H., Kallapur, Suhas G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368156/
https://ncbi.nlm.nih.gov/pubmed/25793992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119281
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