Protection from endotoxic shock in mice by pharmacologic inhibition of phosphatidic acid.
Certain phosphatidic/plasmanic/plasmenic acid (PA) species function as lipid intermediates in cell activation and may function directly as intracellular signaling molecules. PA can also be dephosphorylated to 1,2-diradyl-sn-glycerol by phosphatidate phosphohydrolase. Treatment of various cell types,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43681/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8171002/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.9.3857 |
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