Evaluation of copy number variation and gene expression in neurofibromatosis type-1-associated malignant peripheral nerve sheath tumours

BACKGROUND: Neurofibromatosis type-1 (NF1) is a complex neurogenetic disorder characterised by the development of benign and malignant tumours of the peripheral nerve sheath (MPNSTs). Whilst biallelic NF1 gene inactivation contributes to benign tumour formation, additional cellular changes in gene s...

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Bibliografische gegevens
Gepubliceerd in:Hum Genomics
Hoofdauteurs: Thomas, Laura E, Winston, Jincy, Rad, Ellie, Mort, Matthew, Dodd, Kayleigh M, Tee, Andrew R, McDyer, Fionnuala, Moore, Stephen, Cooper, David N, Upadhyaya, Meena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Primary Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367978/
https://ncbi.nlm.nih.gov/pubmed/25884485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-015-0025-3
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