The effect of adolescent testosterone on hippocampal BDNF and TrkB mRNA expression: relationship with cell proliferation

BACKGROUND: Testosterone attenuates postnatal hippocampal neurogenesis in adolescent male rhesus macaques through altering neuronal survival. While brain-derived neurotropic factor (BDNF)/ tyrosine kinase receptor B (TrkB) are critical in regulating neuronal survival, it is not known if the molecula...

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Bibliographic Details
Published in:BMC Neurosci
Main Authors: Allen, Katherine M, Purves-Tyson, Tertia D, Fung, Samantha J, Shannon Weickert, Cynthia
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367905/
https://ncbi.nlm.nih.gov/pubmed/25886766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-015-0142-x
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