The c.470 T > C CHEK2 missense variant increases the risk of differentiated thyroid carcinoma in the Great Poland population

BACKGROUND: Differentiated thyroid carcinoma (DTC) originates from thyroid follicular epithelial cells and belongs to a group of slowly progressing tumors with a relatively good prognosis. However, recurrences and metastases are a serious problem in advanced stages. Furthermore, progression from a w...

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Bibliographic Details
Published in:Hered Cancer Clin Pract
Main Authors: Kaczmarek-Ryś, Marta, Ziemnicka, Katarzyna, Hryhorowicz, Szymon T, Górczak, Katarzyna, Hoppe-Gołębiewska, Justyna, Skrzypczak-Zielińska, Marzena, Tomys, Michalina, Gołąb, Monika, Szkudlarek, Malgorzata, Budny, Bartłomiej, Siatkowski, Idzi, Gut, Paweł, Ruchała, Marek, Słomski, Ryszard, Pławski, Andrzej
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367841/
https://ncbi.nlm.nih.gov/pubmed/25798211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13053-015-0030-5
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