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Mechanism of actin filament pointed end capping by tropomodulin

Proteins that cap the ends of the actin filament are essential regulators of cytoskeleton dynamics. While several proteins cap the rapidly-growing barbed end, tropomodulin (Tmod) is the only protein known to cap the slowly-growing pointed end. The lack of structural information severely limits our u...

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Publicado en:Science
Main Authors: Rao, Jampani Nageswara, Madasu, Yadaiah, Dominguez, Roberto
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367809/
https://ncbi.nlm.nih.gov/pubmed/25061212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1256159
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