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Inhibition of insulin-like growth factor receptor: end of a targeted therapy?

The Insulin-like Growth Factor 1 (IGF-1) signaling pathway activates several downstream signals important to lung cancer development and survival. IGF-1R activation has been linked to cancer risk in epidemiological studies and tumorigenesis in preclinical models. Several inhibitors of the insulin-li...

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Podrobná bibliografie
Vydáno v:Transl Lung Cancer Res
Hlavní autoři: Pillai, Rathi N., Ramalingam, Suresh S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Pioneer Bioscience Publishing Company 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367644/
https://ncbi.nlm.nih.gov/pubmed/25806201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-6751.2012.11.05
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