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Tumor heterogeneity: evolution through space and time in EGFR mutant non small cell lung cancer patients

NSCLC patients with mutations in epidermal growth factor receptor (EGFR) gene have dramatic responses with the EGFR tyrosine kinase inhibitors (TKI) in the majority of patients. However, all patients will eventually present progression of disease because of both primary and acquired resistance to EG...

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Veröffentlicht in:Transl Lung Cancer Res
Hauptverfasser: Majem, Margarita, Remon, Jordi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Pioneer Bioscience Publishing Company 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367601/
https://ncbi.nlm.nih.gov/pubmed/25806236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-6751.2013.03.09
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