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Tumor heterogeneity: evolution through space and time in EGFR mutant non small cell lung cancer patients

NSCLC patients with mutations in epidermal growth factor receptor (EGFR) gene have dramatic responses with the EGFR tyrosine kinase inhibitors (TKI) in the majority of patients. However, all patients will eventually present progression of disease because of both primary and acquired resistance to EG...

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Pubblicato in:Transl Lung Cancer Res
Autori principali: Majem, Margarita, Remon, Jordi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Pioneer Bioscience Publishing Company 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367601/
https://ncbi.nlm.nih.gov/pubmed/25806236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-6751.2013.03.09
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