Statistical considerations and endpoints for clinical lung cancer studies: Can progression free survival (PFS) substitute overall survival (OS) as a valid endpoint in clinical trials for advanced non-small-cell lung cancer?

In the last decades significant progress has been achieved in the biological understanding of non-small-cell lung cancer (NSCLC) and its tumor heterogeneity has become more evident. The identification of novel tumor targets with different pathways has stimulated the search for anti-tumor agents with...

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Bibliografiske detaljer
Udgivet i:Transl Lung Cancer Res
Main Authors: Pilz, Lothar R, Manegold, Christian, Schmid-Bindert, Gerald
Format: Artigo
Sprog:Inglês
Udgivet: Pioneer Bioscience Publishing Company 2012
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367593/
https://ncbi.nlm.nih.gov/pubmed/25806152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-6751.2011.12.08
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