Donor-Recipient Allele Level HLA-Matching of Unrelated Cord Blood Units Reveals High Degrees of Mismatch and Alters Graft Selection

The feasibility of selecting cord blood (CB) units at high-resolution human leukocyte antigen (HLA)-match has not been investigated. We analyzed the high-resolution donor-recipient HLA-match of 100 double-unit 4–6/6 HLA-A,-B antigen, -DRB1 allele-matched CB grafts (units 1a and 1b) and their back-up...

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Veröffentlicht in:Bone Marrow Transplant
Hauptverfasser: Dahi, Parastoo B., Ponce, Doris M., Devlin, Sean, Evans, Katherine L., Lubin, Marissa, Gonzales, Anne Marie, Byam, Courtney, Sideroff, Melissa, Wells, Deborah, Giralt, Sergio, Kernan, Nancy A., Scaradavou, Andromachi, Barker, Juliet N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367540/
https://ncbi.nlm.nih.gov/pubmed/25000459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2014.135
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