Donor-Recipient Allele Level HLA-Matching of Unrelated Cord Blood Units Reveals High Degrees of Mismatch and Alters Graft Selection

The feasibility of selecting cord blood (CB) units at high-resolution human leukocyte antigen (HLA)-match has not been investigated. We analyzed the high-resolution donor-recipient HLA-match of 100 double-unit 4–6/6 HLA-A,-B antigen, -DRB1 allele-matched CB grafts (units 1a and 1b) and their back-up...

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Pubblicato in:Bone Marrow Transplant
Autori principali: Dahi, Parastoo B., Ponce, Doris M., Devlin, Sean, Evans, Katherine L., Lubin, Marissa, Gonzales, Anne Marie, Byam, Courtney, Sideroff, Melissa, Wells, Deborah, Giralt, Sergio, Kernan, Nancy A., Scaradavou, Andromachi, Barker, Juliet N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367540/
https://ncbi.nlm.nih.gov/pubmed/25000459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2014.135
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