NG2+ Progenitors Derived From Embryonic Stem Cells Penetrate Glial Scar and Promote Axonal Outgrowth Into White Matter After Spinal Cord Injury

The glial scar resulting from spinal cord injury is rich in chondroitin sulfate proteoglycan (CSPG), a formidable barrier to axonal regeneration. We explored the possibility of breaching that barrier by first examining the scar in a functional in vitro model. We found that embryonic stem cell-derive...

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Bibliografiset tiedot
Julkaisussa:Stem Cells Transl Med
Päätekijät: Vadivelu, Sudhakar, Stewart, Todd J., Qu, Yun, Horn, Kevin, Liu, Su, Li, Qun, Silver, Jerry, McDonald, John W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: AlphaMed Press 2015
Aiheet:
Tissue Engineering and Regenerative Medicine
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367502/
https://ncbi.nlm.nih.gov/pubmed/25713464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2014-0107
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