NG2+ Progenitors Derived From Embryonic Stem Cells Penetrate Glial Scar and Promote Axonal Outgrowth Into White Matter After Spinal Cord Injury

The glial scar resulting from spinal cord injury is rich in chondroitin sulfate proteoglycan (CSPG), a formidable barrier to axonal regeneration. We explored the possibility of breaching that barrier by first examining the scar in a functional in vitro model. We found that embryonic stem cell-derive...

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Bibliographic Details
Published in:Stem Cells Transl Med
Main Authors: Vadivelu, Sudhakar, Stewart, Todd J., Qu, Yun, Horn, Kevin, Liu, Su, Li, Qun, Silver, Jerry, McDonald, John W.
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2015
Subjects:
Tissue Engineering and Regenerative Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367502/
https://ncbi.nlm.nih.gov/pubmed/25713464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2014-0107
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