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Tissue engineering a surrogate niche for metastatic cancer cells

In breast and prostate cancer patients, the bone marrow is a preferred site of metastasis. We hypothesized that we could use tissue-engineering strategies to lure metastasizing cancer cells to tissue-engineered bone marrow. First, we generated highly porous 3D silk scaffolds that were biocompatible...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Seib, F. Philipp, Berry, Janice E., Shiozawa, Yusuke, Taichman, Russell S., Kaplan, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367489/
https://ncbi.nlm.nih.gov/pubmed/25771021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.01.076
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