Recognition of Bacterial Signal Peptides by Mammalian Formyl Peptide Receptors: A NEW MECHANISM FOR SENSING PATHOGENS

Formyl peptide receptors (FPRs) are G-protein-coupled receptors that function as chemoattractant receptors in innate immune responses. Here we perform systematic structure-function analyses of FPRs from six mammalian species using structurally diverse FPR peptide agonists and identify a common set o...

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Publicat a:J Biol Chem
Autors principals: Bufe, Bernd, Schumann, Timo, Kappl, Reinhard, Bogeski, Ivan, Kummerow, Carsten, Podgórska, Marta, Smola, Sigrun, Hoth, Markus, Zufall, Frank
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367248/
https://ncbi.nlm.nih.gov/pubmed/25605714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.626747
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