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Oligomerized, filamentous surface presentation of RANTES/CCL5 on vascular endothelial cells
Vascular endothelial cells present luminal chemokines that arrest rolling leukocytes by activating integrins. It appears that several chemokines must form higher-order oligomers to elicit proper in vivo effects, as mutants restricted to forming dimers have lost the ability to recruit leukocytes to s...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367157/ https://ncbi.nlm.nih.gov/pubmed/25791723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09261 |
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