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Molecular origins of synaptotagmin 1 activities on vesicle docking and fusion pore opening
Synaptotagmin 1 (Syt1), a major Ca(2+) sensor in neuroexocytosis, utilizes SNARE- and membrane-binding to regulate vesicle fusion, a required process for neurotransmitter release at the synapse. However, the mechanism by which Syt1 orchestrates SNARE- and membrane- binding to control individual vesi...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366854/ https://ncbi.nlm.nih.gov/pubmed/25791821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09267 |
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