Optimization of multi-epitopic HIV-1 recombinant protein expression in prokaryote system and conjugation to mouse DEC-205 monoclonal antibody: implication for in-vivo targeted delivery of dendritic cells

OBJECTIVE(S): Multi-epitopic protein vaccines and direction of vaccine delivery to dendritic cells (DCs) are promising approaches for enhancing immune responses against mutable pathogens. Escherichia coli is current host for expression of recombinant proteins, and it is important to optimize express...

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Dades bibliogràfiques
Publicat a:Iran J Basic Med Sci
Autors principals: Rahimi, Roghayeh, Ebtekar, Massoumeh, Moazzeni, Seyed Mohammad, Mostafaie, Ali, Mahdavi, Mehdi
Format: Artigo
Idioma:Inglês
Publicat: Mashhad University of Medical Sciences 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366725/
https://ncbi.nlm.nih.gov/pubmed/25810888
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