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ADAMTS13, lucky to have a hydrophobic pocket
In this issue of Blood, de Groot et al identify a hydrophobic pocket in the Cys-rich domain of ADAMTS13 that appears to interact with the hydrophobic pocket in the central A2 domain of von Willebrand factor (VWF) for its proteolysis.(1)
Enregistré dans:
| Publié dans: | Blood |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366622/ https://ncbi.nlm.nih.gov/pubmed/25792731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-621235 |
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