Platelet–Monocyte Aggregate Formation and Mortality Risk in Older Patients With Severe Sepsis and Septic Shock

BACKGROUND. Aging-related changes in platelet and monocyte interactions may contribute to adverse outcomes in sepsis but remain relatively unexamined. We hypothesized that differential platelet–monocyte aggregate (PMA) formation in older septic patients alters inflammatory responses and mortality. M...

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Veröffentlicht in:J Gerontol A Biol Sci Med Sci
Hauptverfasser: Rondina, Matthew T., Carlisle, McKenzie, Fraughton, Tamra, Brown, Samuel M., Miller, Russell R., Harris, Estelle S., Weyrich, Andrew S., Zimmerman, Guy A., Supiano, Mark A., Grissom, Colin K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366600/
https://ncbi.nlm.nih.gov/pubmed/24917177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu082
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