Biosynthesis of proinsulin and insulin in newborn rat pancreas. Interaction of glucose, cyclic AMP, somatostatin, and sulfonylureas on the (3H) leucine incorporation into immunoreactive insulin.

The purpose of the present study was to investigate the regulation of insulin biosynthesis during the perinatal period. The incorporation of [3H]leucine into total immunoreactive insulin (IRI) and into IRI fractions was measured by a specific immunoprecipitation procedure after incubation, extractio...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Garcia, S D, Jarrousse, C, Rosselin, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1976
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436643/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/173741/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108264
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