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Yeast Three-Hybrid Screen Identifies TgBRADIN/GRA24 as a Negative Regulator of Toxoplasma gondii Bradyzoite Differentiation

Differentiation of the protozoan parasite Toxoplasma gondii into its latent bradyzoite stage is a key event in the parasite’s life cycle. Compound 2 is an imidazopyridine that was previously shown to inhibit the parasite lytic cycle, in part through inhibition of parasite cGMP-dependent protein kina...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Odell, Anahi V., Tran, Fanny, Foderaro, Jenna E., Poupart, Séverine, Pathak, Ravi, Westwood, Nicholas J., Ward, Gary E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366382/
https://ncbi.nlm.nih.gov/pubmed/25789621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120331
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