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Repeated Exposure to Ketamine-Xylazine during Early Development Impairs Motor Learning-dependent Dendritic Spine Plasticity in Adulthood

BACKGROUND: Recent studies in rodents suggest that repeated and prolonged anesthetic exposure at early stages of development leads to cognitive and behavioral impairments later in life. However, the underlying mechanism remains unknown. In this study, we tested whether exposure to general anesthesia...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Huang, Lianyan, Yang, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366292/
https://ncbi.nlm.nih.gov/pubmed/25575163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000579
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