Disruption of Escherichia coli Nissle 1917 K5 Capsule Biosynthesis, through Loss of Distinct kfi genes, Modulates Interaction with Intestinal Epithelial Cells and Impact on Cell Health

Escherichia coli Nissle 1917 (EcN) is among the best characterised probiotics, with a proven clinical impact in a range of conditions. Despite this, the mechanisms underlying these "probiotic effects" are not clearly defined. Here we applied random transposon mutagenesis to identify genes...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nzakizwanayo, Jonathan, Kumar, Sandeep, Ogilvie, Lesley A., Patel, Bhavik A., Dedi, Cinzia, Macfarlane, Wendy M., Jones, Brian V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366286/
https://ncbi.nlm.nih.gov/pubmed/25790373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120430
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