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The Structure of SpnF, a Standalone Enzyme that Catalyzes [4+2] Cycloaddition

In the biosynthetic pathway of the spinosyn insecticides, the tailoring enzyme SpnF performs a [4+2]-cycloaddition on a 22-membered macrolactone to forge an embedded cyclohexene ring. To learn more about this reaction, which could potentially proceed through a Diels-Alder mechanism, the 1.50 Å-resol...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Chem Biol
Päätekijät: Fage, Christopher D., Isiorho, Eta A., Liu, Yungnan, Wagner, Drew T., Liu, Hung-wen, Keatinge-Clay, Adrian T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366278/
https://ncbi.nlm.nih.gov/pubmed/25730549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1768
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