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Nuclear Envelope Protein Lem2 is Required for Mouse Development and Regulates MAP and AKT Kinases

The nuclear lamina, along with associated nuclear membrane proteins, is a nexus for regulating signaling in the nucleus. Numerous human diseases arise from mutations in lamina proteins, and experimental models for these disorders have revealed aberrant regulation of various signaling pathways. Previ...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tapia, Olga, Fong, Loren G., Huber, Michael D., Young, Stephen G., Gerace, Larry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366207/
https://ncbi.nlm.nih.gov/pubmed/25790465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116196
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