Identification of Genetic Loci Affecting the Severity of Symptoms of Hirschsprung Disease in Rats Carrying Ednrb(sl) Mutations by Quantitative Trait Locus Analysis

Hirschsprung’s disease (HSCR) is a congenital disease in neonates characterized by the absence of the enteric ganglia in a variable length of the distal colon. This disease results from multiple genetic interactions that modulate the ability of enteric neural crest cells to populate developing gut....

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Veröffentlicht in:PLoS One
Hauptverfasser: Huang, Jieping, Dang, Ruihua, Torigoe, Daisuke, Lei, Chuzhao, Lan, Xianyong, Chen, Hong, Sasaki, Nobuya, Wang, Jinxi, Agui, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366197/
https://ncbi.nlm.nih.gov/pubmed/25790447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122068
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