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Association of TLR5 Gene Polymorphisms in Ulcerative Colitis Patients of North India and Their Role in Cytokine Homeostasis

BACKGROUND AND AIM: In health, TLR signaling protects the intestinal epithelial barrier and in disease, aberrant TLR signaling stimulates diverse inflammatory responses. Association of TLR polymorphisms is ethnicity dependent but how they impact the complex pathogenesis of IBD is not clearly defined...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Meena, Naresh Kumar, Ahuja, Vineet, Meena, Kusumlata, Paul, Jaishree
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366177/
https://ncbi.nlm.nih.gov/pubmed/25789623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120697
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