The Chemokine Platelet Factor-4 Variant (PF-4var)/CXCL4L1 Inhibits Diabetes-Induced Blood–Retinal Barrier Breakdown

PURPOSE. To investigate the expression of platelet factor-4 variant (PF-4var/CXCL4L1) in epiretinal membranes from patients with proliferative diabetic retinopathy (PDR) and the role of PF-4var/CXCL4L1 in the regulation of blood–retinal barrier (BRB) breakdown in diabetic rat retinas and human retin...

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Pubblicato in:Invest Ophthalmol Vis Sci
Autori principali: Abu El-Asrar, Ahmed M., Mohammad, Ghulam, Nawaz, Mohd Imtiaz, Abdelsaid, Mohammed, Siddiquei, Mohammad Mairaj, Alam, Kaiser, Van den Eynde, Kathleen, De Hertogh, Gert, Opdenakker, Ghislain, Al-Shabrawey, Mohamed, Van Damme, Jo, Struyf, Sofie
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365984/
https://ncbi.nlm.nih.gov/pubmed/25711636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-16144
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