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Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice

Immunohistochemical evaluation of serial stored paraffin sections from 42 keratoacanthomas and 11 squamous cell carcinomas demonstrated that skin tumors from UVB-exposed mice showed an inverse relationship (>95%) between p53 protein expression and phospho-Chk1 (Ser317), but not phospho-Chk1 (Ser3...

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Enregistré dans:
Détails bibliographiques
Publié dans:Exp Mol Pathol
Auteurs principaux: Bernard, Jamie J., Lou, You-Rong, Peng, Qing-Yun, Li, Tao, Conney, Allan H., Lu, Yao-Ping
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365929/
https://ncbi.nlm.nih.gov/pubmed/24184701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2013.10.011
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