A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies

DNA methylation plays a fundamental role in the regulation of the genome, but the optimal strategy for analysis of genome-wide DNA methylation data remains to be determined. We developed a comprehensive analysis pipeline for epigenome-wide association studies (EWAS) using the Illumina Infinium Human...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Lehne, Benjamin, Drong, Alexander W, Loh, Marie, Zhang, Weihua, Scott, William R, Tan, Sian-Tsung, Afzal, Uzma, Scott, James, Jarvelin, Marjo-Riitta, Elliott, Paul, McCarthy, Mark I, Kooner, Jaspal S, Chambers, John C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365767/
https://ncbi.nlm.nih.gov/pubmed/25853392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0600-x
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